| OVERALL | HT |
| 2010-05-14 | Bastia | 2 : 0 | Istres | (1:0) |
| 2010-05-07 | Istres | 2 : 1 | Nimes | (1:1) |
| 2010-05-04 | Istres | 2 : 1 | Tours | (1:1) |
| 2010-04-30 | Caen | 1 : 1 | Istres | (1:0) |
| 2010-04-23 | Istres | 1 : 0 | Brest | (1:0) |
| 2010-04-16 | Vannes | 2 : 0 | Istres | (0:0) |
| 2010-04-09 | Istres | 2 : 0 | Strasbourg | (1:0) |
| 2010-04-02 | Sedan | 1 : 1 | Istres | (1:0) |
| 2010-03-26 | Istres | 1 : 3 | Clermont | (1:1) |
| 2010-03-19 | Ajaccio | 1 : 2 | Istres | (0:1) |
| 2010-03-12 | Istres | 1 : 1 | Angers | (1:1) |
| 2010-03-05 | Arles | 3 : 0 | Istres | (2:0) |
| 2010-02-26 | Istres | 2 : 0 | Chateauroux | (1:0) |
| 2010-02-19 | Le Havre | 2 : 1 | Istres | (0:0) |
| 2010-02-12 | Istres | 0 : 2 | Laval | (0:0) |
| 2010-02-05 | Dijon | 1 : 1 | Istres | (1:0) |
| 2010-01-29 | Istres | 1 : 0 | Nantes | (0:0) |
| 2010-01-23 | Tours | 4 : 0 | Istres | (0:0) |
| 2010-01-19 | Guingamp | 0 : 0 | Istres | (0:0) |
| 2010-01-16 | Istres | 2 : 2 | Metz | (0:1) |
| 2009-12-22 | Nimes | 2 : 1 | Istres | (1:0) |
| 2009-12-04 | Istres | 2 : 1 | Caen | (2:0) |
| 2009-12-01 | Brest | 1 : 0 | Istres | (1:0) |
| 2009-11-27 | Istres | 1 : 1 | Vannes | (0:0) |
| 2009-11-06 | Strasbourg | 2 : 0 | Istres | (1:0) |
| 2009-10-30 | Istres | 3 : 1 | Sedan | (2:0) |
| 2009-10-27 | Clermont | 2 : 0 | Istres | (0:0) |
| 2009-10-23 | Istres | 0 : 2 | Ajaccio | (0:1) |
| 2009-10-16 | Angers | 1 : 0 | Istres | (1:0) |
| 2009-10-02 | Istres | 1 : 1 | Arles | (1:0) |
| 2009-09-25 | Chateauroux | 0 : 2 | Istres | (0:1) |
| 2009-09-18 | Istres | 0 : 1 | Le Havre | (0:1) |
| 2009-09-11 | Laval | 2 : 2 | Istres | (1:1) |
| 2009-09-04 | Istres | 0 : 0 | Guingamp | (0:0) |
| 2009-08-28 | Istres | 1 : 1 | Dijon | (1:0) |
| 2009-08-21 | Nantes | 5 : 0 | Istres | (1:0) |
| 2009-08-14 | Metz | 2 : 0 | Istres | (0:0) |
| 2009-08-07 | Istres | 1 : 0 | Bastia | (0:0) |
| HOME | HT |
| 2010-05-07 | Istres | 2 : 1 | Nimes | (1:1) |
| 2010-05-04 | Istres | 2 : 1 | Tours | (1:1) |
| 2010-04-23 | Istres | 1 : 0 | Brest | (1:0) |
| 2010-04-09 | Istres | 2 : 0 | Strasbourg | (1:0) |
| 2010-03-26 | Istres | 1 : 3 | Clermont | (1:1) |
| 2010-03-12 | Istres | 1 : 1 | Angers | (1:1) |
| 2010-02-26 | Istres | 2 : 0 | Chateauroux | (1:0) |
| 2010-02-12 | Istres | 0 : 2 | Laval | (0:0) |
| 2010-01-29 | Istres | 1 : 0 | Nantes | (0:0) |
| 2010-01-16 | Istres | 2 : 2 | Metz | (0:1) |
| 2009-12-04 | Istres | 2 : 1 | Caen | (2:0) |
| 2009-11-27 | Istres | 1 : 1 | Vannes | (0:0) |
| 2009-10-30 | Istres | 3 : 1 | Sedan | (2:0) |
| 2009-10-23 | Istres | 0 : 2 | Ajaccio | (0:1) |
| 2009-10-02 | Istres | 1 : 1 | Arles | (1:0) |
| 2009-09-18 | Istres | 0 : 1 | Le Havre | (0:1) |
| 2009-09-04 | Istres | 0 : 0 | Guingamp | (0:0) |
| 2009-08-28 | Istres | 1 : 1 | Dijon | (1:0) |
| 2009-08-07 | Istres | 1 : 0 | Bastia | (0:0) |
| AWAY | HT |
| 2010-05-14 | Bastia | 2 : 0 | Istres | (1:0) |
| 2010-04-30 | Caen | 1 : 1 | Istres | (1:0) |
| 2010-04-16 | Vannes | 2 : 0 | Istres | (0:0) |
| 2010-04-02 | Sedan | 1 : 1 | Istres | (1:0) |
| 2010-03-19 | Ajaccio | 1 : 2 | Istres | (0:1) |
| 2010-03-05 | Arles | 3 : 0 | Istres | (2:0) |
| 2010-02-19 | Le Havre | 2 : 1 | Istres | (0:0) |
| 2010-02-05 | Dijon | 1 : 1 | Istres | (1:0) |
| 2010-01-23 | Tours | 4 : 0 | Istres | (0:0) |
| 2010-01-19 | Guingamp | 0 : 0 | Istres | (0:0) |
| 2009-12-22 | Nimes | 2 : 1 | Istres | (1:0) |
| 2009-12-01 | Brest | 1 : 0 | Istres | (1:0) |
| 2009-11-06 | Strasbourg | 2 : 0 | Istres | (1:0) |
| 2009-10-27 | Clermont | 2 : 0 | Istres | (0:0) |
| 2009-10-16 | Angers | 1 : 0 | Istres | (1:0) |
| 2009-09-25 | Chateauroux | 0 : 2 | Istres | (0:1) |
| 2009-09-11 | Laval | 2 : 2 | Istres | (1:1) |
| 2009-08-21 | Nantes | 5 : 0 | Istres | (1:0) |
| 2009-08-14 | Metz | 2 : 0 | Istres | (0:0) |
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